Vertigo and Balance - Advanced Balance Lipo Flavonoid (2024)

Reduce the risk of:

related to poor inner ear health*

• Vertigo comfort

  Allison N. - Tullahoma, TN

• One great product in one easy pill

  Joan H. - Boston, MA

• Highly recommend if you get vertigo sometimes

  Greg L. - Lexington, KY

• This works!

  Lewis C. - United States

REFERENCES:

What is it?

1. Balatsouras DG, Koukoutsis G, Fassolis A, Moukos A, Apris A. Benign paroxysmal positional vertigo in the elderly: current insights. Clin Interv Aging. 2018;13:2251-2266
2. Hobeika CP. Equilibrium and Balance in the Elderly. Ear, Nose & Throat Journal. 1999;78(8):558-566. doi:10.1177/014556139907800810
3. Shoair OA, Nyandege AN, Slattum PW. Medication-related dizziness in the older adult. Otolaryngol Clin North Am. 2011 Apr;44(2):455-71, x. doi: 10.1016/j.otc.2011.01.014. PMID: 21474017.
4. Sfakianaki I, Binos P, Karkos P, Dimas GG, Psillas G. Risk Factors for Recurrence of Benign Paroxysmal Positional Vertigo. A Clinical Review. J Clin Med. 2021 Sep 24;10(19):4372. doi: 10.3390/jcm10194372. PMID: 34640391; PMCID: PMC8509726.
5. Jeong SH, Lee SU, Kim JS. Prevention of recurrent benign paroxysmal positional vertigo with vitamin D supplementation: a meta-analysis. J Neurol. 2022 Feb;269(2):619-626. doi: 10.1007/s00415-020-09952-8. Epub 2020 Aug 7. PMID: 32767116.
6. Ginde AA, Liu MC, Camargo CA. Demographic Differences and Trends of Vitamin D Insufficiency in the US Population, 1988-2004. Arch Intern Med. 2009;169(6):626–632. doi:10.1001/archinternmed.2008.604
7. Sokolova L, ho*rr R, Mishchenko T. Treatment of Vertigo: A Randomized, Double-Blind Trial Comparing Efficacy and Safety of Ginkgo biloba Extract EGb 761 and Betahistine. Int J Otolaryngol. 2014;2014:682439. doi: 10.1155/2014/682439. Epub 2014 Jun 25. PMID: 25057270; PMCID: PMC4099171.
8. Wolfgang Issing, Peter Klein, and Michael Weiser. The Homeopathic Preparation Vertigoheel® Versus Ginkgo biloba in the Treatment of Vertigo in an Elderly Population: A Double-Blinded, Randomized, Controlled Clinical Trial. The Journal of Alternative and Complementary Medicine.Feb 2005.155-160.
9. Spiegel R, Kalla R, Mantokoudis G, Maire R, Mueller H, ho*rr R, Ihl R. Ginkgo biloba extract EGb 761® alleviates neurosensory symptoms in patients with dementia: a meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials. Clin Interv Aging. 2018 Jun 13;13:1121-1127. doi: 10.2147/CIA.S157877. PMID: 29942120; PMCID: PMC6005330.

Balance Support Ingredients and Mechanisms of Action

10. “Neurotropic B vitamins play crucial roles as coenzymes and beyond in the nervous system. Particularly vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) contribute essentially to the maintenance of a healthy nervous system. Their importance is highlighted by many neurological diseases related to deficiencies in one or more of these vitamins, but they can improve certain neurological conditions even without a (proven) deficiency”.
11. 6_Calderón-Ospina, C: B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin, CNS Neurosci Ther 2020 Jan;26(1):5-13
12. “The ability of hesperetin to reverse the different inducers of neurodegenerative diseases, including elevated oxidative stress, neuroinflammation, and apoptotic cell death, making hesperetin a candidate drug for the prevention of neurodegenerative conditions”.
13. 7_Khan, A: Antioxidant and Anti-Inflammatory Effects of Citrus Flavonoid Hesperetin: Special Focus on Neurological Disorders, Antioxidants (Basel). 2020 Jul; 9(7): 609
14. “Ginkgo Biloba improves inner ear and cerebral blood flow by decreasing blood viscosity; it also improves mitochondrial function and energy metabolism, which altogether may play a role in improving inner ear and brain function in elderly people with dementia who often have vascular disorders and compromised mitochondrial function”
15. 3_Spiegel R, et al: Ginkgo biloba extract alleviates neurosensory symptoms in patients (with dementia): a meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials. Clin Interv Aging2018 Jun 13; 13:1121-1127
16. “1,25Dihydroxyvitamin D3 (1,25(OH)2D3) the hormonally active form of vitamin D, through its genomic actions, is the major stimulator of active intestinal calcium absorption which involves calcium influx, translocation of calcium through the interior of the enterocyte and basolateral extrusion of calcium by the intestinal plasma membrane pump”.
17. 5_Christakos, S et al: Vitamin D and Intestinal Calcium Absorption Mol Cell Endocrinol. 2011 December 5; 347(1-2): 25–29

Folate & B vitamins

18. Houston DK, Johnson MA, Nozza RJ, Gunter EW, Shea KJ, Cutler GM, Edmonds JT. Age-related hearing loss, vitamin B-12, and folate in elderly women. Am J Clin Nutr. 1999 Mar;69(3):564-71. doi: 10.1093/ajcn/69.3.564. PMID: 10075346.
19. Curhan SG, Stankovic KM, Eavey RD, Wang M, Stampfer MJ, Curhan GC. Carotenoids, vitamin A, vitamin C, vitamin E, and folate and risk of self-reported hearing loss in women. Am J Clin Nutr. 2015 Nov;102(5):1167-75. doi: 10.3945/ajcn.115.109314. Epub 2015 Sep 9. PMID: 26354537; PMCID: PMC4625586.
20. Collaboration HLT. Lowering blood hom*ocysteine with folic acid based supplements: meta- analysis of randomised trials. hom*ocysteine Lowering Trialists' Collaboration. BMJ. 1998 Mar 21;316(7135):894-8. PMID: 9569395; PMCID: PMC28491.
21. Lasisi AO, Fehintola FA, Yusuf OB. Age-related hearing loss, vitamin B12, and folate in the elderly. Otolaryngol Head Neck Surg. 2010 Dec;143(6):826-30. doi: 10.1016/j.otohns.2010.08.031. Epub 2010 Oct 25. PMID: 21109085.
22. Gocer C, et al (2009) hom*ocysteine, Folate and Vitamin B12 Concentrations in Middle Aged Adults Presenting with Sensorineural Hearing Impairment Int. Adv. Otol. 2009; 5:(3) 340-344
23. Karli R, Gül A, Uğur B. Effect of vitamin B12 deficiency on otoacoustic emissions. Acta Otorhinolaryngol Ital. 2013 Aug;33(4):243-7. PMID: 24043911; PMCID: PMC3773962
24. Petridou AI, Zagora ET, Petridis P, Korres GS, Gazouli M, Xenelis I, Kyrodimos E, Kontothanasi G, Kaliora AC. The Effect of Antioxidant Supplementation in Patients with Tinnitus and Normal Hearing or Hearing Loss: A Randomized, Double-Blind, Placebo Controlled Trial. Nutrients. 2019 Dec 12;11(12):3037. doi: 10.3390/nu11123037. PMID: 31842394; PMCID: PMC6950042.

Ginkgo

25. Nguyen T, Alzahrani T. Ginkgo Biloba. [Updated 2022 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541024/#

Vitamin D

26. Sfakianaki I, Binos P, Karkos P, Dimas GG, Psillas G. Risk Factors for Recurrence of Benign Paroxysmal Positional Vertigo. A Clinical Review. J Clin Med. 2021 Sep 24;10(19):4372. doi: 10.3390/jcm10194372. PMID: 34640391; PMCID: PMC8509726.

Bioflavonoids

27. Creston JE, Gillespie MR, Larson AL. Bioflavonoid Therapy in Sensorineural Hearing Loss: A Double-Blind Study. Arch Otolaryngol. 1965;82(2):159–165. doi:10.1001/archotol.1965.00760010161015